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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300331Generated: October 29, 2026

3,5-Dimethoxyaniline → 4-(3,5-Dimethoxyphenylamino)-1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperidine

https://huagongshe.com/reaction/2300331

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DimethoxyanilineHCID 66301—
Reactant[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl-4-piperidoneHCID 22557811—
Product4-(3,5-Dimethoxyphenylamino)-1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperidineHCID 22557810—

Reaction Steps

1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl-4-piperidone (1.40 g) and 3,5-dimethoxyaniline (722 mg) were treated in the same manner as described in Preparation Example 37 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498169B1
Source datasetuspto-grants-2002_12
ORD IDord-045646c11a504b08bf3b23d2a5ddacb1
Source noteuspto-grants-2002_12