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Ethyl 4-amino-1-piperidinecarboxylate → 1-(Ethoxycarbonyl)-4-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methylamino]piperidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 4-amino-1-piperidinecarboxylate | HCID 100867 | — |
| 反応物 | 4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine | HCID 12019237 | — |
| 生成物 | 1-(Ethoxycarbonyl)-4-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methylamino]piperidine | HCID 22558026 | — |
反応手順
4-Amino-1-(ethoxycarbonyl)piperidine (341 mg) and 4-chloromethyl-2-( 3,4,5-trimethoxyphenyl)pyridine (300 mg) were condensed in the same manner as described in Example 2 to give the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06498169B1 |
| 出典データセット | uspto-grants-2002_12 |
| ORD ID | ord-fd24eacda3d4400ebbed838368c9894d |
| 出典メモ | uspto-grants-2002_12 |