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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300360Generated: November 2, 2026

Benzenamine, 3-(methylthio)- → 4-(3-Methylthioanilino)-1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperidine

https://huagongshe.com/reaction/2300360

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenamine, 3-(methylthio)-HCID 15693—
Reactant[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl-4-piperidoneHCID 22557811—
Product4-(3-Methylthioanilino)-1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperidineHCID 22557887—

Reaction Steps

1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]-4-piperidone (1.40 g) and 3-methylthioaniline (655 mg) were reacted in the same manner as described in Preparation Example 37 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498169B1
Source datasetuspto-grants-2002_12
ORD IDord-297bacab5b754019b80500d8c962a247
Source noteuspto-grants-2002_12