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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300368Generated: October 31, 2026

Indan-5-amine → 4-(5-Indanylamino)-1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperidine

https://huagongshe.com/reaction/2300368

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndan-5-amineHCID 90496—
Reactant[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl-4-piperidoneHCID 22557811—
Product4-(5-Indanylamino)-1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperidineHCID 22557857—

Reaction Steps

1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]-4-piperidone (1.40 g) and 5-aminoindan (680 mg) were reacted in the same manner as described in Preparation Example 37 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498169B1
Source datasetuspto-grants-2002_12
ORD IDord-ed49c841db754d0e8be79c88f59dc157
Source noteuspto-grants-2002_12