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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300432Generated: October 31, 2026

1-methyl-1H-imidazole-4-sulfonyl chloride → 3-(3-{[(1-Methyl-1H-imidazole-4-sulfonyl)-(4-thiazol-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid methyl ester

https://huagongshe.com/reaction/2300432

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-methyl-1H-imidazole-4-sulfonyl chlorideHCID 2736887—
Reactant3-{3-[(4-Thiazol-2-yl-benzylamino)-methyl]-phenyl}-propionic acid methyl esterHCID 54285759—
Product3-(3-{[(1-Methyl-1H-imidazole-4-sulfonyl)-(4-thiazol-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid methyl esterHCID 53911579—

Reaction Steps

The title compound of Step B was prepared from 3-{3-[(4-thiazol-2-yl-benzylamino)-methyl]-phenyl}-propionic acid methyl ester, of Step A, and 1-methyl-1H-imidazole-4-sulfonyl chloride following the method described in Example 1, Step B. MS 511 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498172B1
Source datasetuspto-grants-2002_12
ORD IDord-2649e0549fdb413f9338158cf997d7a3
Source noteuspto-grants-2002_12