HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosulfonic acid → 1-Acetyl-2,3-dihydro-1H-indole-5-sulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosulfonic acid | HCID 24638 | — |
| Reactant | 1-acetyl-2,3-dihydro-1H-indole-6-sulfonyl chloride | HCID 10038207 | — |
| Reactant | 1-Acetyl-2,3-dihydro-1H-indole-5-sulfonyl chloride | HCID 14024596 | — |
| Reactant | 1-(2,3-dihydro-1H-isoindol-2-yl)ethan-1-one | HCID 15444356 | — |
| Product | 1-Acetyl-2,3-dihydro-1H-indole-5-sulfonyl chloride | HCID 14024596 | — |
| Product | 2-acetyl-2,3-dihydro-1H-isoindole-5-sulfonyl chloride | HCID 18376540 | — |
Reaction Steps
N-Acetylindoline-5-sulphonyl chloride was prepared by a literature method (A. L. Borrer, E. Chinoporos, M. Filosa, S. R. Herrchen, C. R. Petersen, C. A. Stern, J. Org. Chem. 53, 2047 (1988)) as was N-acetylindoline-6-sulphonyl chloride (P. R. Carlier, M. P. Lockshin, M. P. Filosa, J. Org. Chem. 59, 3232 (1994)). N-Acetylisoindoline-5-sulphonyl chloride was prepared from N-acetylisoindoline and chlorosulphonic acid in analogy to N-acetylindoline-5-sulphonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06498183B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-805b4d6e54ca4493a6e8c3566cbb6362 |
| Source note | uspto-grants-2002_12 |