HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylacetophenone → 1-(3-Methylphenyl)butane-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylacetophenone | HCID 11455 | — |
| Reactant | Propionyl Acetophenone | HCID 21408 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-(3-Methylphenyl)butane-1,3-dione | HCID 14268442 | — |
Reaction Steps
The title compound was prepared (as described above for Intermediate 16) from 2.72 mL of 3′-methylacetophenone and 3.95 mL of EtOAc to yield 2.94 grams of Intermediate 21 as an oil: 1H NMR (400 MHz, CDCl3enol form) δ7.70 (m, 2H), 7.34 (m, 2H), 6.17 (s, 1H), 2.41 (s, 3H), 2.20 (s, 3H); low resolution MS (ES)m/e 177.1 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06498174B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-92030fbefbc9418f89926425f0433a26 |
| Source note | uspto-grants-2002_12 |