Trifluoroacetic acid → HCID 18374598, compound

Participants

Reaction Steps

A solution of 90 mg of tert-butyl (2-{2-[3-(3-butyl-7-dimethylamino-3-ethyl-4-hydroxy-1,1-dioxo-2,3,4,5-tetrahydro-1H-benzo[b]thiepin-5-yl)phenylamino]ethoxy}ethoxy)acetate in 1 ml of methylene chloride and 1 ml of trifluoroacetic acid is stirred for 2 h and then concentrated. The product is purified by HPLC (Knauer Eurospher-100-10-C18, water (0.1% trifluoroacetic acid)/acetonitrile (0.1% trifluoroacetic acid)=80/20→10/90).

Provenance & Evidence