Benzhydrylamine → HCID 18375430, compound

HRID 2300722Notes

Reaction equation

HRID 2300722 reaction equation
CS([C:5]1[N:10]=[C:9]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[N:13]=[CH:12]2)[CH:8]=[CH:7][N:6]=1)(=O)=O.[NH2:20][CH:21]([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[C:22]1([CH:21]([NH:20][C:5]2[N:10]=[C:9]([N:11]3[C:15]4[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=4[N:13]=[CH:12]3)[CH:8]=[CH:7][N:6]=2)[C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 7036BenzhydrylamineHCID 155496402-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine

Product 1

HCID 18375430HCID 18375430, compound

Procedure

2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with aminodiphenylmethane according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (ESI): m/e 378.3 (M+1). 1H NMR (500 MHz, CDCl3): δ partial 8.41 (br s, 1H); 8.24 (br s, 1H); 7.33 (m, 2H); 6.79 (s, 1H); 6.45 (br s, 1H); 6.29 (br s, 1H).

Sources & evidence

ORD record
ord-5fc3e27fef274b4db867bfc169fc679a
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

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