Neopentylamine → HCID 18375966, compound

HRID 2300759Notes

Reaction equation

HRID 2300759 reaction equation
CS([C:5]1[N:10]=[C:9]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[N:13]=[CH:12]2)[CH:8]=[CH:7][N:6]=1)(=O)=O.[CH3:20][C:21]([CH3:25])([CH3:24])[CH2:22][NH2:23]>>[CH3:20][C:21]([CH3:25])([CH3:24])[CH2:22][NH:23][C:5]1[N:10]=[C:9]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[N:13]=[CH:12]2)[CH:8]=[CH:7][N:6]=1

Participants

3

Reactant 2

HCID 79882NeopentylamineHCID 155496402-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine

Product 1

HCID 18375966HCID 18375966, compound

Procedure

2-Methanesulfonyl-4-[benzimidazol-1-yl]pyrimidine was reacted with 2,2-dimethylpropylamine according to the procedure described in EXAMPLE 1, Step C to afford the title compound. Mass Spectrum (CI): 282.2 (M+1). 1H NMR (500 MHz, CDCl3): δ partial 8.66 (s, 1H); 8.39 (br s, 1H); 8.19 (d, J=6.6 Hz, 1H); 7.88 (m, 1H); 7.41 (m, 2H); 6.79 (m, 1H); 5.46 (br s, 1H); 3.40 (d, J=6.4 Hz, 2H); 1.04 (s, 9H).

Sources & evidence

ORD record
ord-256c66f2196544d8b74379652dddd3ba
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

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