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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2300795Generated: October 31, 2026

HCID 135472722, compound → HCID 178422329, compound

https://huagongshe.com/reaction/2300795

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 135472722HCID 135472722—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178422329HCID 17842232992.3%

Reaction Steps

To a solution of 6-Methyl-5-nitrobenzimidazole (300 mg) in THF (35 mL) was added 10% Pd/C (100 mg). The flask was evacuated and charged with H2 several times. The mixture was stirred under a balloon of H2. After 24 h the flask was purged with N2. The catalyst was filtered off and washed with THF. The solvent was removed under reduced pressure giving 230 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06498165B1
Source datasetuspto-grants-2002_12
ORD IDord-56e6aa633c1740f8b7ce648b06ff0fdd
Source noteuspto-grants-2002_12