HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 135472722, compound → HCID 178422329, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 135472722 | HCID 135472722 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178422329 | HCID 178422329 | 92.3% |
Reaction Steps
To a solution of 6-Methyl-5-nitrobenzimidazole (300 mg) in THF (35 mL) was added 10% Pd/C (100 mg). The flask was evacuated and charged with H2 several times. The mixture was stirred under a balloon of H2. After 24 h the flask was purged with N2. The catalyst was filtered off and washed with THF. The solvent was removed under reduced pressure giving 230 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06498165B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-56e6aa633c1740f8b7ce648b06ff0fdd |
| Source note | uspto-grants-2002_12 |