Benzimidazole → 2-[1-(3-Nitrophenyl)ethylamino]-4-[benzimidazol-1-yl]-6-chloropyrimidine

HRID 2300840Notes

Reaction equation

[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]([NH:12][C:13]2[N:18]=[C:17]([Cl:19])[CH:16]=[C:15](Cl)[N:14]=2)[CH3:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].[N:21]1[C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=2[NH:23][CH:22]=1>>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]([NH:12][C:13]2[N:14]=[C:15]([N:21]3[C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=4[N:23]=[CH:22]3)[CH:16]=[C:17]([Cl:19])[N:18]=2)[CH3:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

Reactant 2

HCID 5798Benzimidazole

HCID 18375474HCID 18375474, compound

Product 1

HCID 183757812-[1-(3-Nitrophenyl)ethylamino]-4-[benzimidazol-1-yl]-6-chloropyrimidine

Procedure

The title compound was prepared from 2-[1-(3-nitrophenyl)ethylamino]-4,6-dichloropyrimidine and benzimidazole according to the procedure described in EXAMPLE 306, Step B.

Sources & evidence

ORD record: ord-cf2161a7d02a4d60bfbb56075b7c79db
Source dataset: uspto-grants-2002_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06498165B1

Reaction notes

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