HCID 86758760, compound → HCID 59924788, compound

Participants

Reaction Steps

To a suspension of of 2-[(S)-1-phenylethylamino]-4-[benzimidazol-1-yl]-6-azidopyrimidine (11 mg, 0.03 mmol) in ethanol (1 mL) was added 10% palladium on carbon (11 mg), then the mixture was charged with H2 via balloon. The reaction mixture was stirred for 2 h, then filtered over packed Celite and rinsed thoroughly with EtOAc. The solvent was concentrated under reduced pressure, and the crude material was purified by preparative thin layer chromatography eluting with 3% MeOH/CH2Cl2 to afford 6.2 mg of the title compound. Mass spectrum 331.2 (CI, M+1).

Provenance & Evidence