Selectfluor → HCID 59924714, compound

Participants

Reaction Steps

To a suspension of 2-[(S)-1-phenylethylamino]-4-[benzimidazol-1-yl]pyrimidine (EXAMPLE 1) (10 mg, 0.0317 mmol) in acetonitrile was added Selectfluor™ (17 mg, 0.048 mmol). The reaction mixture was stirred at room temperature for 6 h (it became homogeneous after 2 h), then the solvent was removed in vacuo. The crude material was purified by preparative thin layer chromatography eluting with 1:2 acetone:hexane system to obtain 2.5 mg of the title compound as the only product along with recovered starting material. Mass spectrum 334.2 (M+1).

Provenance & Evidence