3,5-Bis-trifluoromethylphenylboronic acid → HCID 59924913, compound

HRID 2300861Notes

Reaction equation

HRID 2300861 reaction equation
[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23](I)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:26][C:27]([F:42])([F:41])[C:28]1[CH:29]=[C:30](B(O)O)[CH:31]=[C:32]([C:34]([F:37])([F:36])[F:35])[CH:33]=1>>[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23]([C:30]5[CH:31]=[C:32]([C:34]([F:37])([F:35])[F:36])[CH:33]=[C:28]([C:27]([F:26])([F:42])[F:41])[CH:29]=5)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 1562653,5-Bis-trifluoromethylphenylboronic acidHCID 59924653HCID 59924653, compound

Product 1

HCID 59924913HCID 59924913, compound

Procedure

The title compound was prepared according to the procedure described in EXAMPLE 397, starting from 2-[(S)-1-Phenylethylamino]-4-[5-iodobenzimidazol-1-yl]pyrimidine and 3,5-bis(trifluoromethyl)phenyl boronic acid. Mass spectrum (ESI) 528.3 (M+1).

Sources & evidence

ORD record
ord-3d7781390b7b4826be243cd84c46faf6
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

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