3,4,5-Trimethoxybenzeneboronic acid → HCID 59924821, compound

HRID 2300862Notes

Reaction equation

HRID 2300862 reaction equation
[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23](I)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:26][O:27][C:28]1[CH:29]=[C:30](B(O)O)[CH:31]=[C:32]([O:36][CH3:37])[C:33]=1[O:34][CH3:35]>>[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23]([C:30]5[CH:31]=[C:32]([O:36][CH3:37])[C:33]([O:34][CH3:35])=[C:28]([O:27][CH3:26])[CH:29]=5)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 27343903,4,5-Trimethoxybenzeneboronic acidHCID 59924653HCID 59924653, compound

Product 1

HCID 59924821HCID 59924821, compound

Procedure

The title compound was prepared according to the procedure described in EXAMPLE 397, starting from 2-[(S)-1-Phenylethylamino]-4-[5-iodobenzimidazol-1-yl]pyrimidine and 3,4,5-trimethoxyphenyl boronic acid. Mass spectrum (ESI) 415.4 (M+).

Sources & evidence

ORD record
ord-7c59fe86db6d4f02aedee704b2fc46a9
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

Loading…