(3-Amino-4-methylphenyl)boronic acid → HCID 59924824, compound

HRID 2300865Notes

Reaction equation

HRID 2300865 reaction equation
[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23](I)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:26][C:27]1[CH:28]=[C:29](B(O)O)[CH:30]=[CH:31][C:32]=1[CH3:33]>>[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23]([C:29]5[CH:30]=[CH:31][C:32]([CH3:33])=[C:27]([NH2:26])[CH:28]=5)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 2737803(3-Amino-4-methylphenyl)boronic acidHCID 59924653HCID 59924653, compound

Product 1

HCID 59924824HCID 59924824, compound

Procedure

The title compound was prepared according to the procedure described in EXAMPLE 397, starting from 2-[(S)-1-Phenylethylamino]-4-[5-iodobenzimidazol-1-yl]pyrimidine and 3-amino-4-methyl-phenylboronic acid. Mass spectrum (ESI) 421.3 (M+1).

Sources & evidence

ORD record
ord-bdfdd20c2bb9463787fa60a71f169e15
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

Loading…