3-Carboxyphenylboronic acid → HCID 59924746, compound

HRID 2300869Notes

Reaction equation

HRID 2300869 reaction equation
[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[C:22](I)[CH:23]=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:26]([C:29]1[CH:30]=[C:31](B(O)O)[CH:32]=[CH:33][CH:34]=1)([OH:28])=[O:27]>>[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[C:22]([C:33]5[CH:32]=[CH:31][CH:30]=[C:29]([C:26]([OH:28])=[O:27])[CH:34]=5)[CH:23]=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 27339573-Carboxyphenylboronic acidHCID 59924926HCID 59924926, compound

Product 1

HCID 59924746HCID 59924746, compound

Procedure

The title compound was prepared according to the procedure described in EXAMPLE 416, starting from 2-[(S)-1-Phenylethylamino]-4-[6-iodobenzimidazol-1-yl]pyrimidine and 3-carboxyphenylboronic acid. Mass spectrum (ESI) 436.3 (M+1).

Sources & evidence

ORD record
ord-5a56790a2e1445b38faf911e866dae3b
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

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