3-Aminophenylboronic acid → HCID 59924835, compound

HRID 2300871Notes

Reaction equation

HRID 2300871 reaction equation
[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[C:22](I)[CH:23]=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:26][C:27]1[CH:28]=[C:29](B(O)O)[CH:30]=[CH:31][CH:32]=1>>[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[C:22]([C:31]5[CH:30]=[CH:29][CH:28]=[C:27]([NH2:26])[CH:32]=5)[CH:23]=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 922693-Aminophenylboronic acidHCID 59924926HCID 59924926, compound

Product 1

HCID 59924835HCID 59924835, compound

Procedure

The title compound was prepared according to the procedure described in EXAMPLE 416, starting from 2-[(S)-1-Phenylethylamino]-4-[6-iodobenzimidazol-1-yl]pyrimidine and 3-aminophenylboronic acid. Mass spectrum (ESI) 407.3 (M+1).

Sources & evidence

ORD record
ord-9c4a55aeea3e49c593973d45eb365616
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

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