2-Amino-4,6-dichloropyrimidine → HCID 59924942, compound

HRID 2300875Notes

Reaction equation

HRID 2300875 reaction equation
[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23]([Sn](C)(C)C)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:29][C:30]1[N:35]=[C:34](Cl)[CH:33]=[C:32]([Cl:37])[N:31]=1>>[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23]([C:34]5[CH:33]=[C:32]([Cl:37])[N:31]=[C:30]([NH2:29])[N:35]=5)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 655222-Amino-4,6-dichloropyrimidineHCID 69963704HCID 69963704, compound

Product 1

HCID 59924942HCID 59924942, compound

Procedure

The title compound was prepared according to the procedure described in EXAMPLE 424, starting from 2-[(S)-1-Phenylethylamino]-4-[5-trimethylstannylbenzimidazol-1-yl]pyrimidine and 2-amino4,6-dichloropyrimidine. Mass spectrum (ESI) 443.4 (M+).

Sources & evidence

ORD record
ord-bf436070e7734700a27e66fdcb3c3e2a
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

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