2,5-Dichloropyrazine → HCID 59924949, compound

HRID 2300879Notes

Reaction equation

HRID 2300879 reaction equation
[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23]([Sn](C)(C)C)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:29][C:30]1[CH:35]=[N:34][C:33](Cl)=[CH:32][N:31]=1>>[C:1]1([C@@H:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][C:23]([C:33]5[N:34]=[CH:35][C:30]([Cl:29])=[N:31][CH:32]=5)=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Procedure

The title compound was prepared according to the procedure described in EXAMPLE 424, starting from 2-[(S)-1-Phenylethylamino]-4-[5-trimethylstannylbenzimidazol-1-yl]pyrimidine and 2,5-dichloropyrazine. Mass spectrum (ESI) 427.9 (M+).

Sources & evidence

ORD record
ord-2afd723b7f8d403ea6e5d27b4c77bd38
Source dataset
uspto-grants-2002_12
Patent number
US06498165B1

Reaction notes

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