HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-tert.-butyl-2-dimethylaminocarbonyl-5-methoxycarbonylamino-benzenesulfonamide → 2-Dimethylaminocarbonyl-5-methoxycarbonylamino-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-tert.-butyl-2-dimethylaminocarbonyl-5-methoxycarbonylamino-benzenesulfonamide | HCID 15240545 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 2-Dimethylaminocarbonyl-5-methoxycarbonylamino-benzenesulfonamide | HCID 15240548 | 112.2% |
Reaction Steps
1.48 g of N-tert.-butyl-2-dimethylaminocarbonyl-5-methoxycarbonylamino-benzenesulfonamide (Example f) are stirred in 25 ml of trifluoroacetic acid for 18 hours. After the acid has been distilled off, the residue is suspended in toluene. Renewed concentration gives 1.40 g of the sulfonamide; m.p.: 75-77° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06498253B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-032c07415aaf4112b2948482d4e060ee |
| Source note | uspto-grants-2002_12 |