HCID 18377306, compound → HCID 18377295, compound

Participants

Reaction Steps

A 80 μl portion of hydrochloric acid-methanol and 0.1 g of 10% Pd-C were added to 3 ml of ethanol solution containing 93 mg (0.22 mmol) of 3-benzyloxycarbonyl-2,3,4,4a,5,6-hexahydro-6-trifluoroacetyl-1H-pyrazino[1,2-a]quinoxaline, and 3 hours of catalytic hydrogenation was carried out at room temperature. The catalyst was filtered, the solvent was removed by evaporation under a reduced pressure and then the resulting residue was recrystallized from methanol-isopropyl ether to obtain 43 mg (61% in yield) of the title compound.

Provenance & Evidence