1-Indanone → 1-Indanol

Participants

Reaction Steps

1-Indanone (2.5 g, 19 mmol) was dissolved in ethanol (25 ml), and the solution was mixed with sodium borohydride (790 mg, 21 mmol) and stirred at room temperature for 3 hours. The reaction solution was mixed with ethyl acetate, washed with hydrochloric acid (1 N) and saturated brine and dried with anhydrous sodium sulfate, the solvent was removed by evaporation under a reduced pressure, and the thus obtained material was separated and purified by a silica gel column chromatography to obtain 2.4 g (18 mmol, 93%) of the title compound.

Provenance & Evidence