Hydrochloric Acid → 4-(2,3-Dihydro-1H-inden-1-yl)piperidine--hydrogen chloride (1/1)

Participants

Reaction Steps

Ethanol (20 ml), concentrated hydrochloric acid (0.5 ml) and platinum oxide (50 mg) were added to 1-hydroxy-1-pyridin-4-yl-indane (540 mg, 2.6 mmol), and catalytic reduction was carried out at ordinary temperature under ordinary pressure to obtain 420 mg (2.1 mmol, 62% in yield) of the title compound as crystals.

Provenance & Evidence