HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxylamine → Cyanoacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | Water ethanol | HCID 19096565 | — |
| Reactant | 3-(3-Pyridinyl)-2-propenenitrile | HCID 53730136 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Cyanoacetic acid | HCID 9740 | — |
| Product | 3-Pyridinecarboxaldehyde | HCID 10371 | — |
| Product | 3-(3-Pyridinyl)-2-propenenitrile | HCID 53730136 | — |
Reaction Steps
3-(3-pyridyl) acrylic acid amidoxime was prepared by the reaction of 3-(3-pyridyl)-acrylonitrile with hydroxylamine under the usual conditions in ethanol-water solution. The 3-(3-pyridyl)acrylonitrile was obtained from nicotinic aldehyde with cyanoacetic acid in pyridine solution by literature method (J. Am. Chem. Soc. 65, 22(1943)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06500823B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-3b896b314bdf404290df2e2ca6aaf288 |
| Source note | uspto-grants-2002_12 |