2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → 4H-1-Benzopyran-4-one, 2-(4-chlorophenyl)-7-methoxy-

Participants

Reaction Steps

50 mg (0.17 mmol) of 2-(4-chloro-phenyl)-7-methoxy-chroman-4-one synthesized in Preparation 4 and 3.0 molar equivalents (0.12 g, 0.51 mmol) of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone was refuxed in benzene solvent for a day, and then benzene was removed by distillation under reduced pressure. The residue was purified by silica gel column chromatography (eluent: n-hexane/ethylacetate=5/1, v/v) to give the title compound in a yield of 79%.

Provenance & Evidence