p-Bromobenzenesulfonyl chloride → HCID 9871189, compound

Participants

Reaction Steps

100 mg (336 pmol) of 6-amino-2-(benzo[1,3]dioxol-5-yl)-3-hydroxy-4H-chromen-4-one obtained in Example 24 was dissolved in 3 ml of pyridine, and the mixture was reacted with 2 molar equivalents of 4-bromobenzenesulfonylchloride at room temperature for 5 hours. After the reaction was completed, the product was diluted with 10 ml. of water, and the obtained solid was filtered. Then the resulting product was washed with water and ethylether, and dried to give 159 mg of the title compound in a yield of 91.6%.

Provenance & Evidence