反应详情

30 mg (101 pmol) of 6-amino-2-(benzo[1,3]dioxol-5-yl)-3-hydroxy-4H-chromen-4-one obtained in Example 24 was dissolved in 3 ml of pyridine, and the mixture was reacted with excess amount of cyclohexylamino sulfonylchloride at room temperature for 15 hours. After the reaction was completed, the resulting product was diluted with 10 ml of water. The produced solid was filtered, washed with water and ethylether, and then dried to give 6 mg of the title compound in a yield of 13%.

1. filtrationThe produced solid was filtered
2. washwashed with water and ethylether
3. customdried