HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 5-Bromo-8-hydroxyquinoline-7-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 8-Hydroxyquinoline-7-carboxylic Acid | HCID 231363 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-Bromo-8-hydroxyquinoline-7-carboxylic acid | HCID 14534768 | 100.9% |
Reaction Steps
8-Hydroxyquinoline-7-carboxylic acid (1.00 g) is suspended in 25 mL acetic acid. To this is added bromine (0.845 g) dropwise. The mixture is heated to reflux for 1 h, then poured into cold water. The resulting solid is collected, washed with water and dried to yield 1.43 g of the title product as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06500842B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-97ea5eb9b01c4dd294e66517e84b006f |
| Source note | uspto-grants-2002_12 |