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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 230145Generated: October 30, 2026

HCID 70991880, compound → HCID 59834382, compound

https://huagongshe.com/reaction/230145

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 70991880HCID 70991880—
SolventMethanolHCID 887—
SolventSodium MethoxideHCID 10942334—
ProductHCID 59834382HCID 5983438291.4%

Reaction Steps

A mixture of 3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-pyrazolo[4,3-c]pyridine-1-carboxylic acid, tert-butyl ester (14.0 mg) in 3 mL of 0.5 M sodium methoxide solution in methanol was stirred for 30 minutes at room temperature. The resulting solution was concentrated and the residue was extracted with ethyl acetate, washed, dried and concentrated to give 10.0 mg of 3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[4,3-c]pyridine (91% yield). Mass Spec. M+H=356.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07566708B2
Source datasetuspto-grants-2009_07
ORD IDord-87f651bcfd4f4123a757eac81bfdff2c
Source noteuspto-grants-2009_07