HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 70991880, compound → HCID 59834382, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 70991880 | HCID 70991880 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Methoxide | HCID 10942334 | — |
| Product | HCID 59834382 | HCID 59834382 | 91.4% |
Reaction Steps
A mixture of 3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-pyrazolo[4,3-c]pyridine-1-carboxylic acid, tert-butyl ester (14.0 mg) in 3 mL of 0.5 M sodium methoxide solution in methanol was stirred for 30 minutes at room temperature. The resulting solution was concentrated and the residue was extracted with ethyl acetate, washed, dried and concentrated to give 10.0 mg of 3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[4,3-c]pyridine (91% yield). Mass Spec. M+H=356.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07566708B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-87f651bcfd4f4123a757eac81bfdff2c |
| Source note | uspto-grants-2009_07 |