HCID 18373430, compound → HCID 18373545, compound

HRID 2301513Notes

Reaction equation

HRID 2301513 reaction equation
[CH:1]([NH:4][S:5]([C:8]1[C:13]([Cl:14])=[CH:12][CH:11]=[C:10]([N+:15]([O-])=O)[C:9]=1[OH:18])(=[O:7])=[O:6])([CH3:3])[CH3:2].[H][H]>[Pd]>[CH:1]([NH:4][S:5]([C:8]1[C:13]([Cl:14])=[CH:12][CH:11]=[C:10]([NH2:15])[C:9]=1[OH:18])(=[O:7])=[O:6])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 18373430HCID 18373430, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 18373545HCID 18373545, compoundYield 98.4%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Following the general hydrogenation procedure outlined in example 15, N-isopropyl-6-chloro-2-hydroxy-3-nitrobenzenesulfonamide (0.7 g, 2.38 mmol) was reduced with hydrogen and Pd/C (0.7 g) to form the desired product (0.62 g, 98 %). EI-MS m/z 263.5 (M-H)−.

Sources & evidence

ORD record
ord-8cff0ad28d35474e974634598a1ab0dc
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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