Triethylamine → HCID 11494746, compound

Participants

Reaction Steps

A mixture of 2,3-(methylenedioxy)benzoic acid (170mg, 1.02mmol), diphenylphosphoryl azide (338 mg, 1.23 mmol) and triethylamine (0.17mL, 1.23 mmol) was stirred at room temperature for 3 days. The mixture was concentrated. To the residue in 1 mL of N,N-dimethylformamide was added 3-amino-6-chloro-2-hydroxybenzenesulfonamide (40 mg, 0.18 mmol). The resulting mixture was stirred at room temperature for 16 hours. Purification by column chromatography on silica gel, eluting with ethyl acetate/hexane (50/50, v/v), gave the desired product (40 mg, 10%). EI-MS (m/z) 386.2, 388.2 (M−).

Provenance & Evidence