Trifluoroacetic acid → HCID 11613999, compound

Participants

Reaction Steps

A solution of N[3-[N″-[3-(tert-butoxycarbonylamino)propyl]aminosulfonyl]-4-chloro-2-hydroxyphenyl]-N′-(2,3-dichlorophenyl) urea (33 mg, 0.058 mmol) in 1 mL of trifluoroacetic acid was stirred at room temperature for 30 min. The solvent was concentrated. The residue was diluted with methanol, then concentrated. The process was repeated twice to give crude material. Recrystallization from methanol and water produced desired product (23 mg, 68%). EI-MS (m/z) 466.7, 468.8, 470.8 (M−).

Provenance & Evidence