Trifluoroacetic acid → HCID 11541643, compound

Participants

Reaction Steps

Following the general procedure for Boc deprotection outlined in example 36, N-(2-bromophenyl)-N′[3-[N″-[3-(t-butoxycarbonylamino)propyl]aminosulfonyl)-4-chloro-2- hydroxyphenyl] urea (21 mg, 0.036 mmol) was stirred in 1 mL of trifluoroacetic acid to from the desired product (16 mg, 75%). 1H NMR (MeOD-d4): δ 8.28 (d, 1H), 7.80 (d, 1H), 7.59 (d, 1H), 7.33 (t, 1H), 7.07 (d, 1H), 7.02 (d, 1H) 3.05 (m, 4H) 1.87 (m, 2H).

Provenance & Evidence