HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11512586, compound → HCID 11713264, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11512586 | HCID 11512586 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 11713264 | HCID 11713264 | 171.6% |
Reaction Steps
A solution of N-(2-bromophenyl)-N′-[3-[N″-[3-(tert-butoxycarbonylamino)-propyl]aminosulfonyl]-4-chloro-2-hydroxyphenyl] urea (59 mg, 0.102 mmol) in 1 mL of 4.0 M HCl in 1,4-dioxane was stirred at room temperature for 10 min. The solvent was concentrated. Recrystallization from acetone and hexane produced desired product (45 mg, 85%). LC-MS 477.0 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06500863B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-6a52f6d800a34739a56c15f70329acec |
| Source note | uspto-grants-2002_12 |