N-BOC-ethylenediamine → HCID 18373569, compound

Participants

Reaction Steps

Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (1.0 g, 3.44 mmol), t-butyl N-(2-aminoethyl)carbamate (0.5 g, 3.44 mmol) and triethylanine(0.72 mL, 5.16 mmol) were reacted to form the desired product (1.29 g, 90%). 1H NMR (MeOD-d4): δ 7.93 (d, 1H), 7.78 (d, 1H), 3.12 (m, 4H), 1.41 (s, 9H).

Provenance & Evidence