Urea → HCID 11613392, compound

Participants

Reaction Steps

Following the general procedure for urea formation outlined in example 15, N,N-di-(2-methoxyethyl)-3-amino-6-chloro-2-hydroxybenzenesulfonamide (40 mg, 0.12 mmol) and 2,3-dichlorophenylisocyanate (22mg, 0.12 mmol) were coupled to form the desired urea (55 mg, 87%). 1H NMR (MeOD-d4): 8δ 8.27 (m, 1H), 8.03 (m, 1H), 7.23 (m, 2H), 7.03 (m, 1H), 3.61 (m, 4H), 3.45 (m, 4H), 3.23 (s, 6H).

Provenance & Evidence