HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 18373563, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Boc-4-(aminomethyl)piperidine | HCID 736817 | — |
| Reactant | 2,6-Dichloro-3-nitrobenzene-1-sulfonyl chloride | HCID 23447772 | — |
| Product | HCID 18373563 | HCID 18373563 | 79% |
Reaction Steps
Following the general procedure for sulfonamide formation outlined in example 15, 2,6-dichloro-3-nitrobenzenesulfonyl chloride (1.2 g, 4.13 mmol), N-(tert-butoxycarbonyl)4-aminomethyl piperidine (0.88 g, 4.13 mmol) and triethylamine(0.86mL, 6.20 mmol) were reacted to form the desired product (1.52 g, 79%). LC-MS (m/z) 468.2 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06500863B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-b2a9de884360428489a2d37287f47bff |
| Source note | uspto-grants-2002_12 |