HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 18373519, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 18373563 | HCID 18373563 | — |
| Product | HCID 18373519 | HCID 18373519 | 58.2% |
Reaction Steps
Following the general hydrolysis procedure outlined in example 15, N-[(1-tert-butoxycarbonylpiperidin-4-yl)methyl]-2,6dichloro-3-nitrobenzenesulfonamide (800 mg, 1.89 mmol), 60% NaH (227 mg, 5.67 mmol) and water (41 μL, 2.27 mmol) were reacted to form the desired product (495 mg, 58%). EI-MS (m/z) 447.92, 449.84 (M−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06500863B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-8ff327acaab9423ca6d15b4c8ae98350 |
| Source note | uspto-grants-2002_12 |