HCID 18373547, compound → HCID 18373511, compound

HRID 2301608Notes

Reaction equation

HRID 2301608 reaction equation
[Cl:1][C:2]1[C:7]([S:8]([NH:11][CH2:12][CH:13]2[CH2:15][CH2:14]2)(=[O:10])=[O:9])=[C:6]([OH:16])[C:5]([N+:17]([O-])=O)=[CH:4][CH:3]=1.[H][H]>[Pd]>[NH2:17][C:5]1[C:6]([OH:16])=[C:7]([S:8]([NH:11][CH2:12][CH:13]2[CH2:15][CH2:14]2)(=[O:9])=[O:10])[C:2]([Cl:1])=[CH:3][CH:4]=1

Participants

4

Reactant 2

HCID 18373547HCID 18373547, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 18373511HCID 18373511, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Following the general hydrogenation procedure outlined in example 15, 6-chloro-N-cyclopropylmethyl-2-hydroxy-3-nitrobenzenesulfonamide (0.1 g, 3.2 mmol) was reduced with hydrogen and 10% Pd/C (0.1 g) to form the desired product (0.08 g, 89%). LC-MS m/z 277 (M+).

Sources & evidence

ORD record
ord-19daafd1ec274d34a4304efe43bc80e4
Source dataset
uspto-grants-2002_12
Patent number
US06500863B1

Reaction notes

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