反应详情

1 g of moist Raney nickel is added to a solution of 12.5 g of 2-dimethylaminocarbonyl-5-nitrobenzenesulfonamide in 250 ml of methanol, and thorough mixing is carried out at 60° C. under a hydrogen pressure of 50 bar. After the end of uptake of hydrogen, the catalyst is separated off and the filtrate is concentrated, giving 11.0 g of desired product.

1. additionthorough mixing
2. customis carried out at 60° C. under a hydrogen
3. customAfter the end of uptake of hydrogen, the catalyst is separated off
4. concentrationthe filtrate is concentrated