Methyl 5-[2-(3-chlorophenyl)ethenyl]-2-thiophenecarboxylate → HCID 69996930, compound

HRID 2301860Notes

Reaction equation

HRID 2301860 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]2[S:14][C:13]([C:15]([O:17]C)=O)=[CH:12][CH:11]=2)[CH:5]=[CH:6][CH:7]=1.[N:19]12[CH2:26][CH2:25][CH:22]([CH2:23][CH2:24]1)[C@@H:21]([NH:27]C(C1SC(C3N=C(C)SC=3)=CC=1)=O)[CH2:20]2>>[N:19]12[CH2:26][CH2:25][CH:22]([CH2:23][CH2:24]1)[C@@H:21]([NH:27][C:15]([C:13]1[S:14][C:10]([CH:9]=[CH:8][C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=3)=[CH:11][CH:12]=1)=[O:17])[CH2:20]2

Participants

3

Reactant 2

HCID 2740550Methyl 5-[2-(3-chlorophenyl)ethenyl]-2-thiophenecarboxylateHCID 10268544HCID 10268544, compound

Product 1

HCID 69996930HCID 69996930, compoundYield 19%

Procedure

This compound is prepared from methyl 5-[2-(3-chlorophenyl)vinyl]-thiophene-2-carboxylate according to the procedure used to make the compound of Example 31, making non-critical variations. Yield 19%. MS for C20H21ClN2OS (ESI) (M+H)+ m/z 373.

Sources & evidence

ORD record
ord-393e2d2fb2a3462aab2c46a092b98d96
Source dataset
uspto-grants-2002_12
Patent number
US06500840B2

Reaction notes

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