tert-Butyl N-(2-bromoethyl)carbamate → HCID 69978587, compound

HRID 2301963Notes

Reaction equation

HRID 2301963 reaction equation
[C:1]([O:5][C:6](=[O:11])[NH:7][CH2:8][CH2:9]Br)([CH3:4])([CH3:3])[CH3:2].[CH2:12]([O:14][C:15](=[O:28])[CH2:16][CH:17]1[CH2:26][CH2:25][C:24]2[C:19](=[CH:20][CH:21]=[C:22]([OH:27])[CH:23]=2)[CH2:18]1)[CH3:13]>>[CH2:12]([O:14][C:15](=[O:28])[CH2:16][CH:17]1[CH2:26][CH2:25][C:24]2[C:19](=[CH:20][CH:21]=[C:22]([O:27][CH2:9][CH2:8][NH:7][C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:11])[CH:23]=2)[CH2:18]1)[CH3:13]

Participants

3

Reactant 2

HCID 4103526tert-Butyl N-(2-bromoethyl)carbamateHCID 12970188HCID 12970188, compound

Product 1

HCID 69978587HCID 69978587, compound

Procedure

The title compound is prepared according to the procedure of Example 19 except that (2-bromo-ethyl)-carbamic acid tert-butyl ester is used in place of (3-bromo-propyl)-carbamic acid tert-butyl ester and (6-hydroxy-1,2,3,4-tetrahydro-napthalen-2-yl)-acetic acid ethyl ester is used in place of (7-hydroxy-1,2,3,4-tetrahydro-napthalen-2-yl)-acetic acid ethyl ester.

Sources & evidence

ORD record
ord-fc60aac0c86c44dd8a323e79918dc6f2
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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