tert-Butyl N-(2-bromoethyl)carbamate → HCID 69977967, compound

HRID 2301964Notes

Reaction equation

HRID 2301964 reaction equation
[C:1]([O:5][C:6](=[O:11])[NH:7][CH2:8][CH2:9]Br)([CH3:4])([CH3:3])[CH3:2].[CH2:12]([O:14][C:15](=[O:29])[CH2:16][CH:17]1[CH2:23][CH2:22][CH2:21][C:20]2[CH:24]=[C:25]([OH:28])[CH:26]=[CH:27][C:19]=2[CH2:18]1)[CH3:13]>>[CH2:12]([O:14][C:15](=[O:29])[CH2:16][CH:17]1[CH2:23][CH2:22][CH2:21][C:20]2[CH:24]=[C:25]([O:28][CH2:9][CH2:8][NH:7][C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:11])[CH:26]=[CH:27][C:19]=2[CH2:18]1)[CH3:13]

Participants

3

Reactant 2

HCID 4103526tert-Butyl N-(2-bromoethyl)carbamateHCID 69978110HCID 69978110, compound

Product 1

HCID 69977967HCID 69977967, compound

Procedure

The title compound was prepared according to the procedure of Example 19 except that (2-bromo-ethyl)-carbamic acid tert-butyl ester was used in place of (3-bromo-propyl)-carbamic acid tert-butyl ester and (2-hydroxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)-acetic acid ethyl ester was used in place of (7-hydroxy-1,2,3,4-tetrahydro-napthalen-2-yl)-acetic acid ethyl ester and the title compound was isolated as a pale yellow oil.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-60c0361e2a844b9e9c226d5d6a336680
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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