tert-butyl N-(4-bromobutyl)carbamate → HCID 69978046, compound

HRID 2301965Notes

Reaction equation

HRID 2301965 reaction equation
[C:1]([O:5][C:6](=[O:13])[NH:7][CH2:8][CH2:9][CH2:10][CH2:11]Br)([CH3:4])([CH3:3])[CH3:2].[CH2:14]([O:16][C:17](=[O:31])[CH2:18][CH:19]1[CH2:25][CH2:24][CH2:23][C:22]2[CH:26]=[C:27]([OH:30])[CH:28]=[CH:29][C:21]=2[CH2:20]1)[CH3:15]>>[CH2:14]([O:16][C:17](=[O:31])[CH2:18][CH:19]1[CH2:25][CH2:24][CH2:23][C:22]2[CH:26]=[C:27]([O:30][CH2:11][CH2:10][CH2:9][CH2:8][NH:7][C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:13])[CH:28]=[CH:29][C:21]=2[CH2:20]1)[CH3:15]

Participants

3

Reactant 2

HCID 10868765tert-butyl N-(4-bromobutyl)carbamateHCID 69978110HCID 69978110, compound

Product 1

HCID 69978046HCID 69978046, compound

Procedure

The title compound was prepared according to the procedure of Example 19 except that (4-bromo-butyl)-carbamic acid tert-butyl ester was used in place of (3-bromo-propyl)-carbamic acid tert-butyl ester and (2-hydroxy-6,7,8,9-tetrahydro-5H-benzo-cyclohepten-6-yl)-acetic acid ethyl ester was used in place of (7-hydroxy-1,2,3,4-tetrahydro-napthalen-2-yl)-acetic acid ethyl ester.

Sources & evidence

ORD record
ord-08b7778336f74d468dea792be769c981
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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