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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2301966Generated: October 25, 2026

tert-Butyl N-(2-bromoethyl)carbamate → [3-(2-tert-Butoxycarbonylamino-ethoxy)-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl]-acetic Acid Ethyl Ester

https://huagongshe.com/reaction/2301966

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl N-(2-bromoethyl)carbamateHCID 4103526—
Reactant(3-hydroxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)-acetic acid ethyl esterHCID 69978135—
Product[3-(2-tert-Butoxycarbonylamino-ethoxy)-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl]-acetic Acid Ethyl EsterHCID 69978639—

Reaction Steps

The title compound is prepared according to the procedure of Example 19 except that (2-bromo-ethyl)-carbamic acid tert-butyl ester is used in place of (3-bromo-propyl)-carbamic acid tert-butyl ester and (3-hydroxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)-acetic acid ethyl ester is used in place of (7-hydroxy-1,2,3,4-tetrahydro-napthalene-2-yl)-acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06429214B1
Source datasetuspto-grants-2002_08
ORD IDord-53b4f8c88f1f4b51abc2222a9ae92b07
Source noteuspto-grants-2002_08