Methyl Acetate → HCID 69978616, compound

HRID 2301976Notes

Reaction equation

HRID 2301976 reaction equation
[CH3:1][O:2][C:3](=[O:24])[CH2:4][C:5]1[C:6](=[O:23])[N:7]([CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([OH:15])[CH:9]=2.COC(=O)C.[C:30]([O:34][C:35](=[O:41])[NH:36][CH2:37][CH2:38][CH2:39]Br)([CH3:33])([CH3:32])[CH3:31]>>[CH3:1][O:2][C:3](=[O:24])[CH2:4][C:5]1[C:6](=[O:23])[N:7]([CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([O:15][CH2:39][CH2:38][CH2:37][NH:36][C:35]([O:34][C:30]([CH3:31])([CH3:33])[CH3:32])=[O:41])[CH:9]=2

Participants

4

Reactant 3

HCID 6584Methyl AcetateHCID 4460490tert-butyl N-(3-bromopropyl)carbamateHCID 69977982(1-Benzyl-7-hydroxy-2-oxo-1,2-dihydro-quinolin-3-yl)-acetic acid methyl ester

Product 1

HCID 69978616HCID 69978616, compound

Procedure

The title compound was prepared using the procedure of Example 75 and (1-benzyl-7-hydroxy-2-oxo-1,2-dihydro-quinolin-3-yl)-acetic acid methyl ester in place of 7-hydroxy-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)acetic acid methyl ester and (3-bromopropyl)carbamic acid tert-butyl ester in place of (2-bromoethyl)carbamic acid tert-butyl ester.

Sources & evidence

ORD record
ord-3e3b8c90638947babdf81c8e5751fda5
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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