HCID 18462590, compound → [1-Benzyl-7-(3-aminopropoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester

HRID 2301978Notes

Reaction equation

HRID 2301978 reaction equation
COC(=O)CC1CC2C(=CC(OCCNC(OC(C)(C)C)=O)=CC=2)NC1=O.[CH3:28][O:29][C:30](=[O:62])[CH2:31][C:32]1[C:33](=[O:61])[N:34]([CH2:54][C:55]2[CH:60]=[CH:59][CH:58]=[CH:57][CH:56]=2)[C:35]2[C:40]([CH:41]=1)=[CH:39][CH:38]=[C:37]([O:42][CH2:43][CH2:44][CH2:45][NH:46]C(OC(C)(C)C)=O)[CH:36]=2>>[CH3:28][O:29][C:30](=[O:62])[CH2:31][C:32]1[C:33](=[O:61])[N:34]([CH2:54][C:55]2[CH:60]=[CH:59][CH:58]=[CH:57][CH:56]=2)[C:35]2[C:40]([CH:41]=1)=[CH:39][CH:38]=[C:37]([O:42][CH2:43][CH2:44][CH2:45][NH2:46])[CH:36]=2

Participants

3

Reactant 2

HCID 18462590HCID 18462590, compoundHCID 69978616[7-(3-tert-Butoxycarbonylaminopropoxy)-1-benzyl-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester

Product 1

HCID 69978057[1-Benzyl-7-(3-aminopropoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester

Procedure

The title compound is prepared according to the procedure of Example 78 except that [7-(2-tert-butoxycarbonylamino-ethoxy)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-acetic acid methyl ester is replaced with [7-(3-tert-butoxycarbonylaminopropoxy)-1-benzyl-2-oxo-1,2-dihydro-quinolin-3-yl]acetic acid methyl ester.

Sources & evidence

ORD record
ord-b891ca8409d6490ba8d0aadd2ef42e41
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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