[1-Benzyl-7-(3-aminopropoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester → [1-Benzyl-7-(3-amino-propoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]-acetic Acid

HRID 2301981Notes

Reaction equation

HRID 2301981 reaction equation
FC(F)(F)C(O)=O.COC(=O)CC1CC2C(=CC(OCCCNC(N)=N)=CC=2)NC1=O.C[O:33][C:34](=[O:59])[CH2:35][C:36]1[C:37](=[O:58])[N:38]([CH2:51][C:52]2[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=2)[C:39]2[C:44]([CH:45]=1)=[CH:43][CH:42]=[C:41]([O:46][CH2:47][CH2:48][CH2:49][NH2:50])[CH:40]=2>>[CH2:51]([N:38]1[C:39]2[C:44](=[CH:43][CH:42]=[C:41]([O:46][CH2:47][CH2:48][CH2:49][NH2:50])[CH:40]=2)[CH:45]=[C:36]([CH2:35][C:34]([OH:59])=[O:33])[C:37]1=[O:58])[C:52]1[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=1

Participants

3

Reactant 2

HCID 69978057[1-Benzyl-7-(3-aminopropoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl EsterHCID 178499389HCID 178499389, compound

Product 1

HCID 18462630[1-Benzyl-7-(3-amino-propoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]-acetic Acid

Procedure

The title compound was prepared according to the procedure of Example 84 except that [7-(3-guanidino-propoxy)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-acetic acid methyl ester trifluoroacetate was replaced with [1-benzyl-7-(3-aminopropoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic acid methyl ester.

Sources & evidence

ORD record
ord-13823d5e804642118b89e581c5237cb8
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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